Rab22a sting

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August undefined, 2024

WebIntercellular transfer of activated STING triggered by RAB22A-mediated non-canonical autophagy promotes antitumor immunity. Cell Res. 2024; 32(12):1086-1104 (ISSN: 1748 … WebcGAS-STING 信号通路发现史（上）. 写在前面：现在想快速发文章，踩热点是不二法门，而cGAS-STING信号通路堪称宇宙最火的天然免疫信号通路，搭上了这辆车顺利发表的文章不计其数。. 系列文章主要浅显地谈一下cGAS-STING信号通路的发家之路。. 本篇文章集中在模式 …

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Web2024年10月24日，中山大学肿瘤防治中心研究团队在《细胞研究》（Cell Research）上发表题为“RAB22A介导的非经典自噬调控激活型STING的胞间转移促进抗肿瘤免疫”的文章。该研究命名了一种新型细胞器Rafeesome（RA… WebMar 1, 2024 · To determine whether Rab22a is involved in CSFV proliferation, we first examined the effect of Rab22a overexpression on virus replication. As shown in Fig. 2 A … poundland redhill opening times

Rab22a-NeoF1: a promising target for osteosarcoma patients

WebOct 24, 2024 · STING V155M or STING R281Q levels in EVPs, but not their intracellular levels, could be increased by both RAB22A WT and RAB22A Q64L (Fig. 3f and … WebMar 1, 2001 · Plays a role in endocytosis and intracellular protein transport. Mediates trafficking of TF from early endosomes to recycling endosomes ( PubMed: 16537905 ). Required for NGF-mediated endocytosis of NTRK1, and subsequent neurite outgrowth ( PubMed: 21849477 ). Binds GTP and GDP and has low GTPase activity. Alternates … WebOct 30, 2024 · 同时，rab22a 使 rab7 失活以抑制rafeesome 与溶酶体的融合，从而使带有活化 sting 的自噬体的内囊泡分泌成为一种新型的细胞外囊泡，我们将其定义为 r-ev（rab22a 诱导的细胞外囊泡）。活化的含有 sting 的 r-ev 诱导受体细胞向肿瘤微环境释放 ifnβ，从而促进 … tours for seniors australia

Rab22a-NeoF1 fusion protein promotes osteosarcoma …

cGAS-STING 信号通路发现史（上） - 知乎 - 知乎专栏

WebIntercellular transfer of activated STING triggered by RAB22A-mediated non-canonical autophagy promotes antitumor immunity. Cell ... PubMed ID: 36280710 DOI: 10.1038/s41422-022-00731-w. Luo X, Wang J, Lu J, Wang X, Miao Y, Li Q, Li X, Wang L. Rab22a Promotes Epithelial-Mesenchymal Transition in Papillary Thyroid Carcinoma by … WebJun 1, 2024 · Exon–intron-fused RAB22A regulates metastasis of osteosarcoma. Liao et al. show that protein products resulting from chromosomal translocations involving RAB22A mediate release of GTP-bound RhoA ... tours for sa georgeWebNov 7, 2024 · Synopsis. Recycling endosomes are transient tubular intermediates that maintain cellular/organelle homeostasis. Rab22A promotes the assembly of a BLOC-1-BLOC-2-KIF13A complex on sorting endosomes to generate the recycling tubular endosomes that are required for the biogenesis of lysosome-related organelles. Rab22A … tours for senior citizens south africa

"WebJun 4, 2004 · Rab22a Is Associated with the Recycling Endosome and Not the Incoming Clathrin-independent Endosome. The tubular endosomes containing MHCI also have Arf6 associated with them and have been implicated in the recycling of MHCI back to the PM (Radhakrishna and Donaldson, 1997; Caplan et al., 2002; Naslavsky et al., 2003). " - Rab22a sting

Rab22a sting

Li ZHONG Research Associate undergraduate student Sun Yat …

WebMar 21, 2024 · RAB22A (RAB22A, Member RAS Oncogene Family) is a Protein Coding gene. Diseases associated with RAB22A include Exocervical Carcinoma.Among its related … WebActivated STING-containing R-EVs induce IFNβ release from recipient cells to the tumor microenvironment, promoting antitumor immunity. Consistently, RAB22A enhances the …

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WebNational Center for Biotechnology Information WebMar 14, 2024 · Rab22a is a novel prognostic marker for cell progression in breast cancer. He M, Shen L, Jiang C, Gao G, Wang K, Jiao Y, Sun L, Cui Y, Ke Z, Yang ZHe M, et al. Int J Mol …

WebApr 2, 2024 · miR-204-5p acts as a tumor suppressor in colorectal cancer through inhibiting RAB22A and reveal RAB22A to be a new oncogene and prognostic factor for colorectal cancer. Exposure of human breast cancer cells to hypoxia augments microvesicle (MVs) shedding that is mediated by the HIF-dependent expression of the small GTPase RAB22A, … WebFeb 22, 2024 · 外泌体Rab22a- NeoF1融合蛋白可通过其供体细胞的结合伴侣PYK2激活RhoA来促进其阴性受体癌细胞的肺转移。因此，该外泌体Rab22a-NeoF1融合蛋白促进了其受体骨肉瘤细胞的肺转移，可以通过使用设计的RGD肽破坏其与PYK2的相互作用来靶向该过程，实现肺转移的抑制作用。

WebFeb 11, 2024 · Here, we report that osteosarcoma Rab22a-NeoF1 fusion protein, ... Intercellular transfer of activated STING triggered by RAB22A-mediated non-canonical … WebHere, we report that activated STING could be transferred between cells to promote antitumor immunity, a process triggered by RAB22A-mediated non-canonical autophagy. …

WebIntercellular transfer of activated STING triggered by RAB22A-mediated non-canonical autophagy promotes antitumor immunity. Rab22A promotes the assembly of a BLOC-1 …

WebOct 24, 2024 · STING V155M or STING R281Q levels in EVPs, but not their intracellular levels, could be increased by both RAB22A WT and RAB22A Q64L (Fig. 3f and … poundland redditch opening timesWeb近日，相关论文以《RAB22A 介导的非典型自噬触发激活型 STING 的细胞间传递促进抗肿瘤免疫》（Intercellular transfer of activated STING triggered by RAB22A-mediated non-canonical autophagy promotes antitumor immunity）为题发表在 Cell Research 上，高瑛是第一作者，康铁邦和魏灯辉博士担任共同通讯作者 [1]。 poundland redexWebIntercellular transfer of activated STING triggered by RAB22A-mediated non-canonical autophagy promotes antitumor immunity. Cell ... PubMed ID: 36280710 DOI: … tours for single womenWebMar 1, 2024 · To determine whether Rab22a is involved in CSFV proliferation, we first examined the effect of Rab22a overexpression on virus replication. As shown in Fig. 2 A and C, the PK-15 cells transfected with exogenous Rab22a showed significantly increased levels of Rab22a compared with the control cells. The results of real-time PCR and … tours for single travelersRas-related protein Rab-22A is a protein that in humans is encoded by the RAB22A gene. The protein encoded by this gene is a member of the RAB family of small GTPases. The GTP-bound form of the encoded protein has been shown to interact with early-endosomal antigen 1, and may be involved in the trafficking o… poundland ravensthorpeWebSep 1, 2024 · However, the role of Rab22a during the intracellular transport of these proteins has been studied in non-specialized cells. Only recently the function of Rab22a has been … tours for san franciscoWebDec 7, 2024 · Consistently, RAB22A enhances the antitumor effect of the STING agonist diABZI in mice, and a high RAB22A level predicts good survival in nasopharyngeal cancer … poundland references